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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
27.58
Human Site:
T393
Identified Species:
37.92
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
T393
M
T
E
A
Q
L
S
T
A
V
I
E
N
P
E
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
T393
M
T
E
A
Q
L
S
T
A
V
I
E
N
P
E
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
A514
T
E
A
Q
L
S
T
A
V
I
E
N
P
E
M
Dog
Lupus familis
XP_543550
1017
111618
T393
M
T
E
A
Q
L
S
T
A
V
I
E
N
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
T393
M
T
E
A
Q
L
S
T
A
V
I
E
N
P
E
Rat
Rattus norvegicus
NP_001129232
1015
111665
T393
M
T
E
A
Q
L
S
T
A
V
I
E
N
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
T393
M
T
E
A
Q
L
S
T
T
I
I
E
N
P
E
Frog
Xenopus laevis
Q8QFR2
1013
112021
N393
T
T
E
P
Q
L
P
N
T
V
I
E
N
P
E
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
T393
T
M
E
S
Q
L
S
T
T
I
I
E
N
P
E
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
S393
T
N
T
E
P
Q
L
S
T
T
I
I
E
N
P
Fruit Fly
Dros. melanogaster
O17468
1047
113397
V390
G
L
G
K
S
A
P
V
L
E
H
P
Q
R
L
Honey Bee
Apis mellifera
XP_001122939
838
91355
M239
Y
L
V
S
A
H
A
M
N
G
G
G
P
T
A
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
C336
T
V
M
D
F
A
W
C
G
R
N
L
L
A
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
H365
D
G
S
A
A
N
F
H
F
E
V
K
E
L
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
P393
Q
A
N
L
V
E
S
P
A
Q
L
L
L
E
T
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
S241
Y
F
R
R
P
S
W
S
P
D
G
Q
H
I
A
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
L391
S
E
E
N
D
K
A
L
Q
K
Y
G
G
S
R
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
N.A.
86.6
66.6
66.6
6.6
0
0
0
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
N.A.
93.3
66.6
80
13.3
0
13.3
0
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
6.6
N.A.
13.3
0
6.6
P-Site Similarity:
N.A.
20
N.A.
20
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
6
42
12
12
12
6
36
0
0
0
0
6
12
% A
% Cys:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
6
% C
% Asp:
6
0
0
6
6
0
0
0
0
6
0
0
0
0
0
% D
% Glu:
0
12
53
6
0
6
0
0
0
12
6
48
12
12
48
% E
% Phe:
0
6
0
0
6
0
6
0
6
0
0
0
0
0
0
% F
% Gly:
6
6
6
0
0
0
0
0
6
6
12
12
6
0
6
% G
% His:
0
0
0
0
0
6
0
6
0
0
6
0
6
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
18
53
6
0
6
0
% I
% Lys:
0
0
0
6
0
6
0
0
0
6
0
6
0
0
0
% K
% Leu:
0
12
0
6
6
48
6
6
6
0
6
12
12
6
6
% L
% Met:
36
6
6
0
0
0
0
6
0
0
0
0
0
0
6
% M
% Asn:
0
6
6
6
0
6
0
6
6
0
6
6
48
6
0
% N
% Pro:
0
0
0
6
12
0
12
6
6
0
0
6
12
48
6
% P
% Gln:
6
0
0
6
48
6
0
0
6
6
0
6
6
0
0
% Q
% Arg:
0
0
6
6
0
0
0
0
0
6
0
0
0
6
6
% R
% Ser:
6
0
6
12
6
12
48
12
0
0
0
0
0
6
0
% S
% Thr:
30
42
6
0
0
0
6
42
24
6
0
0
0
6
6
% T
% Val:
0
6
6
0
6
0
0
6
6
36
6
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _